A Model for Simulation of Infant Cardiovascular Response to Orthostatic Stress

نویسندگان

  • Yutaka Nobuaki
  • Akira Amano
  • Takao Shimayoshi
  • Jianyin Lu
  • Eun Bo Shim
  • Tetsuya Matsuda
چکیده

We developed an infant circulation model which incorporates an accurate myocardial cell model including a beta adrenergic system. The beta adrenergic system is essential for the response reproduction of the baroreflex control system. The proposed model was constructed by modifying the parameters of a human adult circulation model with the aid of a guinea pig myocardial cell model, whose baseline heart rate is close to that of an infant. The presented model is in good agreement with results obtained in physiological experiments.

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تاریخ انتشار 2007